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Antibody therapeutics targeting ion channels: are we there yet?

The combination of technological advances, genomic sequences and market success is catalyzing rapid development of antibody-based therapeutics. Cell surface receptors and ion channel proteins are well known drug targets, but the latter has seen less success. The availability of crystal structures, b...

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Bibliografiske detaljer
Main Authors: Sun, Han, Li, Min
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4011603/
https://ncbi.nlm.nih.gov/pubmed/23381110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2012.202
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