Functional analysis of MKP-1 and MKP-2 in breast cancer tamoxifen sensitivity

Increased activation of ERK signaling has been reported in breast cancer models of acquired tamoxifen resistance. Here, we examined the expression of Mitogen-Activated Protein Kinase Phosphatases (MKPs) 1 and 2 following tamoxifen treatment and the effects of MKP-1/MKP-2 overexpression on tamoxifen...

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Detalhes bibliográficos
Main Authors: Haagenson, Kelly K., Zhang, Jessica Wei, Xu, Zhengfan, Shekhar, Malathy P.V., Wu, Gen Sheng
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2014
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4011587/
https://ncbi.nlm.nih.gov/pubmed/24658355
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