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Enabling Hyperpolarized (129)Xe MR Spectroscopy and Imaging of Pulmonary Gas Transfer to the Red Blood Cells in Transgenic Mice Expressing Human Hemoglobin
PURPOSE: Hyperpolarized (HP) (129)Xe gas in the alveoli can be detected separately from (129)Xe dissolved in pulmonary barrier tissues (blood plasma and parenchyma) and red blood cells (RBCs) of humans, allowing this isotope to probe impaired gas uptake. Unfortunately, mice, which are favored as lun...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4011488/ https://ncbi.nlm.nih.gov/pubmed/24006177 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mrm.24915 |
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