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A cell free system for functional centromere and kinetochore assembly Authors

This protocol describes a cell free system to study vertebrate centromere and kinetochore formation. We reconstitute tandem arrays of centromere protein A (CENP-A) nucleosomes as a substrate for centromere and kinetochore assembly. These chromatin substrates are immobilized on magnetic beads and the...

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Bibliografiske detaljer
Main Authors: Guse, Annika, Fuller, Colin J., Straight, Aaron F.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4011387/
https://ncbi.nlm.nih.gov/pubmed/23018190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nprot.2012.112
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