Dose findings of antofloxacin hydrochloride for treating bacterial infections in an early clinical trial using PK-PD parameters in healthy volunteers

AIM: To find an appropriate dose regimen of the novel antibacterial agent antofloxacin for a phase II clinical trial using a population pharmacokinetic (PPK) study in healthy volunteers and the minimum inhibitory concentration (MIC) as pharmacodynamic (PD) parameters. METHODS: Twenty-four healthy vo...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Li, Yun-fei, Wang, Kun, Yin, Fang, He, Ying-chun, Huang, Ji-han, Zheng, Qing-shan
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4011355/
https://ncbi.nlm.nih.gov/pubmed/22864303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2012.68
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados