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Population pharmacokinetics of modafinil acid and estimation of the metabolic conversion of modafinil into modafinil acid in 5 major ethnic groups of China

AIM: To describe the population pharmacokinetic profile of modafinil acid and to compare the extent of metabolism of modafinil into modafinil acid in 5 major ethnic groups (Han, Mongolian, Korean, Uygur, and Hui) of China. METHODS: In a multi-center, open-label, single dose clinical trial, 49 health...

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Detalhes bibliográficos
Main Authors: Wu, Ke-hua, Guo, Tao, Deng, Chen-hui, Guan, Zheng, Li, Liang, Zhou, Tian-yan, Lu, Wei
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4011351/
https://ncbi.nlm.nih.gov/pubmed/23103618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2012.124
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