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Tissue plasminogen activator attenuates ventilator-induced lung injury in rats

AIM: To test the hypothesis that the tissue plasminogen activator (tPA) may counteract the inhibitory effect of plasminogen activator inhibitors (PAI) and attenuate lung injury in a rat model of ventilator-induced lung injury (VILI). METHODS: Adult male Sprague-Dawley rats were ventilated with a HVZ...

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Detalhes bibliográficos
Main Authors: Huang, Liang-ti, Chou, Hsiu-chu, Wang, Leng-fang, Chen, Chung-ming
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4011324/
https://ncbi.nlm.nih.gov/pubmed/22796762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2012.66
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