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Efficacy of zoledronic acid in treatment of teoarthritis is dependent on the disease progression stage in rat medial meniscal tear model

AIM: To investigate whether the stage of osteoarthritis (OA) progression influenced the efficacy of the third-generation bisphosphonate zoledronic acid in a rat medial meniscal tear model. METHODS: Medial meniscal tear (MMT) was surgically induced in adult male Sprague Dawley rats. Zoledronic acid (...

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Bibliografski detalji
Glavni autori: Yu, De-gang, Yu, Bo, Mao, Yuan-qing, Zhao, Xin, Wang, Xiao-qing, Ding, Hui-feng, Cao, Lei, Liu, Guang-wang, Nie, Shao-bo, Liu, Shen, Zhu, Zhen-an
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2012
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4011147/
https://ncbi.nlm.nih.gov/pubmed/22609837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2012.28
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