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Iron-Regulated Protein HupB of Mycobacterium tuberculosis Positively Regulates Siderophore Biosynthesis and Is Essential for Growth in Macrophages

Mycobacterium tuberculosis expresses the 28-kDa protein HupB (Rv2986c) and the Fe(3+)-specific high-affinity siderophores mycobactin and carboxymycobactin upon iron limitation. The objective of this study was to understand the functional role of HupB in iron acquisition. A hupB mutant strain of M. t...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Pandey, Satya Deo, Choudhury, Mitali, Yousuf, Suhail, Wheeler, Paul R., Gordon, Stephen V., Ranjan, Akash, Sritharan, Manjula
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2014
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4010995/
https://ncbi.nlm.nih.gov/pubmed/24610707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.01483-13
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