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Essential Role for the Response Regulator PmrA in Coxiella burnetii Type 4B Secretion and Colonization of Mammalian Host Cells

Successful host cell colonization by the Q fever pathogen, Coxiella burnetii, requires translocation of effector proteins into the host cytosol by a Dot/Icm type 4B secretion system (T4BSS). In Legionella pneumophila, the two-component system (TCS) PmrAB regulates the Dot/Icm T4BSS and several addit...

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Detalhes bibliográficos
Main Authors: Beare, Paul A., Sandoz, Kelsi M., Larson, Charles L., Howe, Dale, Kronmiller, Brent, Heinzen, Robert A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4010987/
https://ncbi.nlm.nih.gov/pubmed/24610709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.01532-14
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