The unique insert of cellular and viral fms protein tyrosine kinase domains is dispensable for enzymatic and transforming activities.

The receptors for colony stimulating factor-1 (CSF-1), platelet derived growth factor and the c-kit protein tyrosine kinase (PTK) contain within their catalytic domains a stretch of 60-100 residues, largely unrelated in sequence, with no counterpart in other PTKs. Of the 64 amino acids within this k...

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Detalhes bibliográficos

Publicado no:	EMBO J
Principais autores:	Taylor, G R, Reedijk, M, Rothwell, V, Rohrschneider, L, Pawson, T
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Publishing Group 1989
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC401083/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2551672/ https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1989.tb03611.x
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