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Correlation of measured and calculated serum osmolality during mannitol or hypertonic saline infusion in patients after craniotomy: a study protocol and statistical analysis plan for a randomised controlled trial

INTRODUCTION: Brain oedema is a major complication after craniotomy. Hyperosmolar agents have been used as the medical treatment for this condition. Measurement and estimation of serum osmolality during hyperosmolar agent infusion is of clinical importance to evaluate clinical efficacy, adjust dosag...

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Autors principals: Li, Qian, Xu, Ming, Zhou, Jian-Xin
Format: Artigo
Idioma:Inglês
Publicat: BMJ Publishing Group 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4010815/
https://ncbi.nlm.nih.gov/pubmed/24760352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bmjopen-2014-004921
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