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Cellular Mechanisms of Tissue Fibrosis. 6. Purinergic signaling and response in fibroblasts and tissue fibrosis

Tissue fibrosis occurs as a result of the dysregulation of extracellular matrix (ECM) synthesis. Tissue fibroblasts, resident cells responsible for the synthesis and turnover of ECM, are regulated via numerous hormonal and mechanical signals. The release of intracellular nucleotides and their result...

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Autors principals: Lu, David, Insel, Paul A.
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4010809/
https://ncbi.nlm.nih.gov/pubmed/24352335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00381.2013
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