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Oxalate upregulates expression of IL-2Rβ and activates IL-2R signaling in HK-2 cells, a line of human renal epithelial cells

The role of inflammation in oxalate-induced nephrolithiasis is debated. Our gene expression study indicated an increase in interleukin-2 receptor β (IL-2Rβ) mRNA in response to oxalate (Koul S, Khandrika L, Meacham RB, Koul HK. PLoS ONE 7: e43886, 2012). Herein, we evaluated IL-2Rβ expression and it...

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Autors principals: Koul, Sweaty, Khandrika, Lakshmipathi, Pshak, Thomas J., Iguchi, Naoko, Pal, Mintu, Steffan, Joshua J., Koul, Hari K.
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4010678/
https://ncbi.nlm.nih.gov/pubmed/24523387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00462.2013
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