Dissection of a Ciona regulatory element reveals complexity of cross-species enhancer activity

Vertebrate genomes share numerous conserved non-coding elements, many of which function as enhancer elements and are hypothesised to be under evolutionary constraint due to a need to be bound by combinations of sequence-specific transcription factors. In contrast, few such conserved elements can be...

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Bibliografiske detaljer
Main Authors: Chen, Wei-Chung, Pauls, Stefan, Bacha, Jamil, Elgar, Greg, Loose, Matthew, Shimeld, Sebastian M.
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2014
Fag:
Evolution of Developmental Control Mechanisms
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4010673/
https://ncbi.nlm.nih.gov/pubmed/24680932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2014.03.013
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