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Expression of normal and translocated c-myc alleles in Burkitt's lymphoma cells: evidence for different regulation.

In Burkitt's lymphoma (BL) cells the normal c-myc allele is usually silent or expressed at very low levels. Here we demonstrate that the normal c-myc allele can be induced in BL cells by 12-O-tetradecanoylphorbol-13-acetate (TPA). TPA did activate the normal c-myc alleles in Raji(P207), BL36, P...

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Bibliographic Details
Main Authors: Eick, D, Bornkamm, G W
Format: Artigo
Language:Inglês
Published: 1989
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC401061/
https://ncbi.nlm.nih.gov/pubmed/2551669
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