Targeting Staphylococcus aureus Quorum Sensing with Nonpeptidic Small Molecule Inhibitors

[Image: see text] A series of 3-oxo-C(12)-HSL, tetramic acid, and tetronic acid analogues were synthesized to gain insights into the structural requirements for quorum sensing inhibition in Staphylococcus aureus. Compounds active against agr were noncompetitive inhibitors of the autoinducing peptide...

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Xehetasun bibliografikoak
Egile Nagusiak: Murray, Ewan J., Crowley, Rebecca C., Truman, Alex, Clarke, Simon R., Cottam, James A., Jadhav, Gopal P., Steele, Victoria R., O’Shea, Paul, Lindholm, Catharina, Cockayne, Alan, Chhabra, Siri Ram, Chan, Weng C., Williams, Paul
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Chemical Society 2014
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4010551/
https://ncbi.nlm.nih.gov/pubmed/24592914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm500215s
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