The Immunosuppressant Protosappanin A Diminished Recipient T Cell Migration into Allograft via Inhibition of IP-10 in Rat Heart Transplant

The immunosuppressant Protosappanin A (PrA), isolated from the medicinal herb, promotes cardiac allograft survival, diminishes inflammatory cell infiltration, and inhibits interferon γ-induced protein 10 kDa (IP-10) mRNA expression in rats cardiac grafts. Binding of the chemokine IP-10 to its cognat...

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Detalhes bibliográficos
Main Authors: Zhang, Maomao, He, Jieqiong, Hou, Jingbo, Wu, Jian, Sun, Meng, Cui, Jinjin, Tian, Jiangtian, Jiang, Miaomiao, Yu, Bo
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4010525/
https://ncbi.nlm.nih.gov/pubmed/24798458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0096138
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