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Apamin Does Not Inhibit Human Cardiac Na(+) Current, L-type Ca(2+) Current or Other Major K(+) Currents

BACKGROUND: Apamin is commonly used as a small-conductance Ca(2+)-activated K(+) (SK) current inhibitor. However, the specificity of apamin in cardiac tissues remains unclear. OBJECTIVE: To test the hypothesis that apamin does not inhibit any major cardiac ion currents. METHODS: We studied human emb...

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Detalhes bibliográficos
Main Authors: Yu, Chih-Chieh, Ai, Tomohiko, Weiss, James N., Chen, Peng-Sheng
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4010514/
https://ncbi.nlm.nih.gov/pubmed/24798465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0096691
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