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Synthesis and Evaluation of Fluorine-Substituted Phenyl Acetate Derivatives as Ultra-Short Recovery Sedative/Hypnotic Agents

BACKGROUND: Soft drugs are molecules that are purposefully designed to be rapidly metabolized (metabolically labile). In anesthesia, the soft drug is useful because it enables precise titration to effect and rapid recovery, which might allow swift and clear-headed recovery of consciousness and early...

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Autors principals: Zhang, Heng, Xu, Xiangqing, Chen, Yin, Qiu, Yinli, Liu, Xin, Liu, Bi-Feng, Zhang, Guisen
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4010497/
https://ncbi.nlm.nih.gov/pubmed/24796695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0096518
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