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Continuing a Cancer Treatment Despite Tumor Growth May Be Valuable: Sunitinib in Renal Cell Carcinoma as Example

BACKGROUND: The US FDA and the EMA have approved seven agents for the treatment of renal cell carcinoma, primarily based on differences in progression-free survival (PFS). Because PFS is an arbitrary endpoint we hypothesized that an analysis would demonstrate the growth rate of tumors remained const...

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Autors principals: Burotto, Mauricio, Wilkerson, Julia, Stein, Wilfred, Motzer, Robert, Bates, Susan, Fojo, Tito
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4010463/
https://ncbi.nlm.nih.gov/pubmed/24796484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0096316
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