Phenotypic T Cell Exhaustion in a Murine Model of Bacterial Infection in the Setting of Pre-Existing Malignancy

While much of cancer immunology research has focused on anti-tumor immunity both systemically and within the tumor microenvironment, little is known about the impact of pre-existing malignancy on pathogen-specific immune responses. Here, we sought to characterize the antigen-specific CD8(+) T cell r...

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Détails bibliographiques
Auteurs principaux: Mittal, Rohit, Wagener, Maylene, Breed, Elise R., Liang, Zhe, Yoseph, Benyam P., Burd, Eileen M., Farris, Alton B., Coopersmith, Craig M., Ford, Mandy L.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2014
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4010417/
https://ncbi.nlm.nih.gov/pubmed/24796533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0093523
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