Melatonin reduces acute lung inflammation, edema, and hemorrhage in heatstroke rats

AIM: To assess the therapeutic effect of melatonin on heat-induced acute lung inflammation and injury in rats. METHODS: Heatstroke was induced by exposing anesthetized rats to heat stress (36 °C, 100 min). Rats were treated with vehicle or melatonin (0.2, 1, 5 mg/kg) by intravenous administration 10...

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Main Authors: Wu, Wen-shiann, Chou, Ming-ting, Chao, Chien-ming, Chang, Chen-kuei, Lin, Mao-tsun, Chang, Ching-ping
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2012
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Original Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4010375/
https://ncbi.nlm.nih.gov/pubmed/22609835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2012.29
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