Combined administration of anisodamine and neostigmine produces anti-shock effects: involvement of α7 nicotinic acetylcholine receptors

AIM: To evaluate the anti-effects of anisodamine and neostigmine in animal models of endotoxic and hemorrhagic shock. METHODS: Kunming mice were injected with lipopolysaccharide (LPS 30 mg/kg, ip) to induce endotoxic shock. Anisodamine (12.5, 25, and 50 mg/kg, ip) and neostigmine (12.5, 25, and 50 μ...

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Autors principals: Sun, Li, Zhang, Gu-fang, Zhang, Xin, Liu, Qing, Liu, Jian-guo, Su, Ding-feng, Liu, Chong
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2012
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4010367/
https://ncbi.nlm.nih.gov/pubmed/22580739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2012.26
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