Diabetes-Induced Impairment in Visual Function in Mice: Contributions of p38 MAPK, RAGE, Leukocytes, and Aldose Reductase

PURPOSE. Visual function is impaired in diabetes, but molecular causes of this dysfunction are not clear. We assessed effects of diabetes on visual psychophysics in mice, and tested the effect of therapeutic approaches reported previously to inhibit vascular lesions of the retinopathy. METHODS. We u...

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Main Authors: Lee, Chieh Allen, Li, Guangyuan, Patel, Mansi D., Petrash, J. Mark, Benetz, Beth Ann, Veenstra, Alex, Amengual, Jaume, von Lintig, Johannes, Burant, Christopher J., Tang, Johnny, Kern, Timothy S.
Formato: Artigo
Idioma:Inglês
Publicado em: The Association for Research in Vision and Ophthalmology 2014
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4010365/
https://ncbi.nlm.nih.gov/pubmed/23920367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.13-11659
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