Inhibition of hypoxia inducible factor-1α ameliorates lung injury induced by trauma and hemorrhagic shock in rats

AIM: Ischemia/reperfusion is an initial triggering event that leads to gut-induced acute lung injury (ALI). In this study, we investigated whether hypoxia inducible factor-1α (HIF-1α) played a role in the pathogenesis of lung injury induced by trauma and hemorrhagic shock (T/HS). METHODS: Male Wista...

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Autors principals: Jiang, Hong, Huang, Yan, Xu, Hui, Hu, Rong, Li, Qi-fang
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2012
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4010356/
https://ncbi.nlm.nih.gov/pubmed/22465950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2012.5
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