Stereoselective binding of mexiletine and ketoprofen enantiomers with human serum albumin domains

AIM: To investigate the stereoselective binding of mexiletine or ketoprofen enantiomers with different recombinant domains of human serum albumin (HSA). METHODS: Three domains (HSA DOM I, II and III) were expressed in Pichia pastoris GS115 cells. Blue Sepharose 6 Fast Flow was employed to purify the...

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Detalhes bibliográficos
Main Authors: Shi, Da, Jin, Yin-xiu, Tang, Yi-hong, Hu, Hai-hong, Xu, Si-yun, Yu, Lu-shan, Jiang, Hui-di, Zeng, Su
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4010353/
https://ncbi.nlm.nih.gov/pubmed/22555373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2012.8
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