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A High-throughput Screening Assay for Determining Cellular Levels of Total Tau Protein

The microtubule-associated protein (MAP) tau has been implicated in the pathology of numerous neurodegenerative diseases. In the past decade, the hyperphosphorylated and aggregated states of tau protein have been important targets in the drug discovery field for the potential treatment of Alzheimer’...

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Detalhes bibliográficos
Main Authors: Dehdashti, Seameen J., Zheng, Wei, Gever, Joel R., Wilhelm, Robert, Nguyen, Dac-Trung, Sittampalam, Gurusingham, McKew, John C., Austin, Christopher P., Prusiner, Stanley B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4010324/
https://ncbi.nlm.nih.gov/pubmed/23905996
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