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Glycyrrhizin attenuates rat ischemic spinal cord injury by suppressing inflammatory cytokines and HMGB1

AIM: To investigate the neuroprotective effect of glycyrrhizin (Gly) against the ischemic injury of rat spinal cord and the possible role of the nuclear protein high-mobility group box 1 (HMGB1) in the process. METHODS: Male Sprague-Dawley rats were subjected to 45 min aortic occlusion to induce tra...

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Detalhes bibliográficos
Main Authors: Gong, Gu, Yuan, Li-bang, Hu, Ling, Wu, Wei, Yin, Liang, Hou, Jing-li, Liu, Ying-hai, Zhou, Le-shun
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4010273/
https://ncbi.nlm.nih.gov/pubmed/22158106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2011.151
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