Frequency of CYP2C9 alleles in Koreans and their effects on losartan pharmacokinetics

AIM: CYP2C9 enzyme metabolizes numerous clinically important drugs. The aim of this study is to investigate the frequencies of CYP2C9 genotypes and the effects of selected alleles on losartan pharmacokinetics in a large sample of the Korean population. METHODS: The CYP2C9 gene was genotyped in 1796...

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Main Authors: Bae, Jung-woo, Choi, Chang-ik, Kim, Mi-jeong, Oh, Da-hee, Keum, Seul-ki, Park, Jung-in, Kim, Bo-hye, Bang, Hye-kyoung, Oh, Sung-gon, Kang, Byung-sung, Park, Hyun-joo, Kim, Hae-deun, Ha, Ji-hey, Shin, Hee-jung, Kim, Young-hoon, Na, Han-sung, Chung, Myeon-woo, Jang, Choon-gon, Lee, Seok-yong
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2011
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Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4010224/
https://ncbi.nlm.nih.gov/pubmed/21841812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2011.100
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