VEGF ameliorates tubulointerstitial fibrosis in unilateral ureteral obstruction mice via inhibition of epithelial-mesenchymal transition

AIM: Vascular endothelial growth factor (VEGF) has been shown to be a survival factor for renal tubular epithelial cells. In the present study, we investigated whether administration of VEGF ameliorates tubulointerstitial fibrosis in a mouse model of unilateral ureteral obstruction (UUO). METHODS: T...

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Detalhes bibliográficos
Main Authors: Lian, Yao-guo, Zhou, Qiu-gen, Zhang, Ying-juan, Zheng, Fa-lei
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4010218/
https://ncbi.nlm.nih.gov/pubmed/21986574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2011.111
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