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Control of Mycobacterium tuberculosis infection by a subset of lung parenchyma homing CD4 T cells

SUMMARY: Th1 cells are critical for containment of Mycobacterium tuberculosis (Mtb) infection, but little else is known about the properties of protective CD4 T cell responses. Here we show that pulmonary Th1 response against Mtb is composed of two populations that are either CXCR3(hi) and localize...

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Detalhes bibliográficos
Main Authors: Sakai, Shunsuke, Kauffman, Keith D., Schenkel, Jason M., McBerry, Cortez C., Mayer-Barber, Katrin D., Masopust, David, Barber, Daniel L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4010124/
https://ncbi.nlm.nih.gov/pubmed/24591367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1400019
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