Effects of Rhein Lysinate on H(2)O(2)-induced cellular senescence of human umbilical vascular endothelial cells

AIM: To observe the effect of Rhein lysinate (RHL) on cellular senescence of human umbilical vascular endothelial cells (HUVECs) and elucidate its action mechanism. METHODS: Cell viability was determined using MTT assay. The expression levels of Sirt1 mRNA and protein were measured by RT-PCR and Wes...

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Autori principali: Lin, Ya-jun, Zhen, Yong-zhan, Wei, Jie, Liu, Bo, Yu, Zong-yuan, Hu, Gang
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2011
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4010073/
https://ncbi.nlm.nih.gov/pubmed/21909125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2011.101
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