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Drug discovery for polycystic kidney disease

In polycystic kidney disease (PKD), a most common human genetic diseases, fluid-filled cysts displace normal renal tubules and cause end-stage renal failure. PKD is a serious and costly disorder. There is no available therapy that prevents or slows down the cystogenesis and cyst expansion in PKD. Nu...

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Detalhes bibliográficos
Main Authors: Sun, Ying, Zhou, Hong, Yang, Bao-xue
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4009953/
https://ncbi.nlm.nih.gov/pubmed/21642949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2011.29
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