Kynurenic acid attenuates multiorgan dysfunction in rats after heatstroke

AIM: To assess whether systemic delivery of kynurenic acid improves the outcomes of heatstroke in rats. METHODS: Anesthetized rats were divided into 2 major groups and given vehicle solution (isotonic saline 0.3 mL/kg rat weight) or kynurenic acid (30–100 mg in 0.3 mL saline/kg) 4 h before the start...

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Autors principals: Hsieh, Yi-chang, Chen, Ruei-feng, Yeh, Yi-shian, Lin, Mao-tsun, Hsieh, Jui-hsiang, Chen, Sheng-hsien
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2011
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4009940/
https://ncbi.nlm.nih.gov/pubmed/21293468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2010.191
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