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Genome-wide analysis of microRNA and mRNA expression signatures in hydroxycamptothecin-resistant gastric cancer cells

AIM: To investigate the involvement of microRNAs (miRNAs) in intrinsic drug resistance to hydroxycamptothecin (HCPT) of six gastric cancer cell lines (BGC-823, SGC-7901, MGC-803, HGC-27, NCI-N87, and AGS). METHODS: A sulforhodamine B (SRB) assay was used to analyze the sensitivity to HCPT of six gas...

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Detalhes bibliográficos
Main Authors: Wu, Xue-mei, Shao, Xiang-qiang, Meng, Xian-xin, Zhang, Xiao-na, Zhu, Li, Liu, Shi-xu, Lin, Jian, Xiao, Hua-sheng
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4009939/
https://ncbi.nlm.nih.gov/pubmed/21293479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2010.204
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