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Free Energy Profile of APOBEC3G Protein Calculated by a Molecular Dynamics Simulation
The human APOBEC3G protein (A3G) is a single-stranded DNA deaminase that inhibits the replication of retrotransposons and retroviruses, including HIV-1. Atomic details of A3G’s catalytic mechanism have started to emerge, as the structure of its catalytic domain (A3Gctd) has been revealed by NMR and...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
MDPI
2012
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4009775/ https://ncbi.nlm.nih.gov/pubmed/24832225 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biology1020245 |
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