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The transcriptional activation function located in the hormone-binding domain of the human oestrogen receptor is not encoded in a single exon.

Using GAL4 chimeric receptors, we have reported previously that the hormone-binding domain (HBD) of the human oestrogen receptor (hER) contains an hormone-inducible transcription activation function. We have extended that study here to show that this activation function represents the major activati...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Veröffentlicht in:EMBO J
Hauptverfasser: Webster, N J, Green, S, Tasset, D, Ponglikitmongkol, M, Chambon, P
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 1989
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC400972/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2767048/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1989.tb03526.x
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