Osteoclast-gene expression profiling reveals osteoclast-derived CCR2 chemokines promoting myeloma cell migration

Multiple myeloma (MM) is characterized by the clonal expansion of malignant plasma cells (multiple myeloma cells, MMC), primarily in the bone marrow (BM). Osteolytic bone lesions are detected in 80% of patients, due to increased osteoclastic bone resorption and reduced osteoblastic bone formation. M...

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Bibliographische Detailangaben
Hauptverfasser: Moreaux, Jérôme, Hose, Dirk, Kassambara, Alboukadel, Rème, Thierry, Moine, Philippe, Requirand, Guilhem, Goldschmidt, Hartmut, Klein, Bernard
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Hematology 2011
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4009699/
https://ncbi.nlm.nih.gov/pubmed/21097672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-04-279760
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