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Substance P up-regulates macrophage inflammatory protein-1 β expression in human T lymphocytes

Substance P (SP) is an important modulator of neuroimmunoregulation. We have demonstrated that human T lymphocytes express SP and neurokinin-1 receptor (NK-1R), a primary SP receptor. In the present study, we investigated whether SP stimulates synthesis of macrophage inflammatory protein-1β (MIP-1β)...

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Detalhes bibliográficos
Main Authors: Guo, Chang-Jiang, Lai, Jian-Ping, Luo, Hong-Mei, Douglas, Steven D., Ho, Wen-Zhe
Formato: Artigo
Idioma:Inglês
Publicado em: 2002
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4009682/
https://ncbi.nlm.nih.gov/pubmed/12458047
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