Human atrial natriuretic peptide receptor defines a new paradigm for second messenger signal transduction.

We isolated cDNAs encoding a 115 kd human atrial natriuretic peptide (alpha ANP) receptor (ANP-A receptor) that possesses guanylate cyclase activity, by low-stringency hybridization with sea urchin Arbacia punctulata membrane guanylate cyclase probes. The human ANP-A receptor has a 32 residue signal...

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Bibliographic Details
Main Authors: Lowe, D G, Chang, M S, Hellmiss, R, Chen, E, Singh, S, Garbers, D L, Goeddel, D V
Format: Artigo
Language:Inglês
Published: 1989
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC400964/
https://ncbi.nlm.nih.gov/pubmed/2569967
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