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Site-specific insertion of selenium into the redox-active disulfide of the flavoprotein Augmenter of Liver Regeneration

Augmenter of liver regeneration (sfALR) is a small disulfide-bridged homodimeric flavoprotein with sulfhydryl oxidase activity. Here, we investigate the catalytic and spectroscopic consequences of selectively replacing C145 by a selenocysteine to complement earlier studies in which random substituti...

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Detalhes bibliográficos
Main Authors: Schaefer-Ramadan, Stephanie, Thorpe, Colin, Rozovsky, Sharon
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4009370/
https://ncbi.nlm.nih.gov/pubmed/24582598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2014.02.001
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