The Role of TPA I/D and PAI-1 4G/5G Polymorphisms in Multiple Sclerosis

Background. Previous studies have shown impaired fibrinolysis in multiple sclerosis (MS) and implicated extracellular proteolytic enzymes as important factors in demyelinating neuroinflammatory disorders. Tissue-type plasminogen activator (t-PA) and its inhibitor (PAI-1) are key molecules in both fi...

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Hauptverfasser: Živković, Maja, Starčević Čizmarević, Nada, Lovrečić, Luca, Klupka-Sarić, Inge, Stanković, Aleksandra, Gašparović, Iva, Lavtar, Polona, Dinčić, Evica, Stojković, Ljiljana, Rudolf, Gorazd, Šega Jazbec, Saša, Perković, Olivio, Sinanović, Osman, Sepčić, Juraj, Kapović, Miljenko, Peterlin, Borut, Ristić, Smiljana
Format: Artigo
Sprache:Inglês
Veröffentlicht: Hindawi Publishing Corporation 2014
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4009184/
https://ncbi.nlm.nih.gov/pubmed/24825926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/362708
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