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The Role of TPA I/D and PAI-1 4G/5G Polymorphisms in Multiple Sclerosis
Background. Previous studies have shown impaired fibrinolysis in multiple sclerosis (MS) and implicated extracellular proteolytic enzymes as important factors in demyelinating neuroinflammatory disorders. Tissue-type plasminogen activator (t-PA) and its inhibitor (PAI-1) are key molecules in both fi...
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| Autors principals: | , , , , , , , , , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Hindawi Publishing Corporation
2014
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4009184/ https://ncbi.nlm.nih.gov/pubmed/24825926 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/362708 |
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