Interferon (IFN)-γ-mediated inflammation and the kynurenine pathway in relation to bone mineral density: the Hordaland Health Study

The risk of osteoporosis increases in inflammatory disorders. In cell-mediated immune activation, interferon (IFN)-γ stimulates macrophage release of neopterin and increases the activity of indoleamine 2,3-dioxygenase (IDO), thereby stimulating tryptophan degradation along the kynurenine pathway. Pl...

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Autores principales: Apalset, E M, Gjesdal, C G, Ueland, P M, Midttun, Ø, Ulvik, A, Eide, G E, Meyer, K, Tell, G S
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley & Sons Ltd 2014
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4008990/
https://ncbi.nlm.nih.gov/pubmed/24528145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cei.12288
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