The RNA binding protein La influences both the accuracy and the efficiency of RNA polymerase III transcription in vitro.

The autoantigen La binds the U-rich 3' ends of all nascent RNA polymerase III transcripts. Here, we demonstrate that this abundant nuclear phosphoprotein not only binds these RNAs but appears to be required for their synthesis. HeLa cell extracts immunochemically depleted of La by either patient or...

Descrizione completa

Dettagli Bibliografici

Pubblicato in:	EMBO J
Autori principali:	Gottlieb, E, Steitz, J A
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Nature Publishing Group 1989
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC400883/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2498086/ https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1989.tb03445.x
Tags:	Aggiungi Tag Nessun Tag, puoi essere il primo ad aggiungerne!!