Efficacy and tolerability of controlled-release oxycodone for oxaliplatin-induced peripheral neuropathy and the extension of FOLFOX therapy in advanced colorectal cancer patients

BACKGROUND: The oxaliplatin-based regimen FOLFOX is widely used to treat patients with advanced colorectal cancer (CRC). However, dose-limiting toxicity after continuous oxaliplatin administration can lead to peripheral neuropathy. Several agents, including opioids, that have been employed to treat...

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Hlavní autoři: Nagashima, Makoto, Ooshiro, Mitsuru, Moriyama, Ayako, Sugishita, Yui, Kadoya, Kengo, Sato, Ayami, Kitahara, Tomoaki, Takagi, Ryuichi, Urita, Tasuku, Yoshida, Yutaka, Tanaka, Hiroshi, Oshiro, Takashi, Okazumi, Shinichi, Katoh, Ryoji
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer Berlin Heidelberg 2014
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4008774/
https://ncbi.nlm.nih.gov/pubmed/24452412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00520-014-2132-4
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