Submicron-Bubble-Enhanced Focused Ultrasound for Blood–Brain Barrier Disruption and Improved CNS Drug Delivery

The use of focused ultrasound (FUS) with microbubbles has been proven to induce transient blood–brain barrier opening (BBB-opening). However, FUS-induced inertial cavitation of microbubbles can also result in erythrocyte extravasations. Here we investigated whether induction of submicron bubbles to...

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Bibliographic Details
Main Authors: Fan, Ching-Hsiang, Liu, Hao-Li, Ting, Chien-Yu, Lee, Ya-Hsuan, Huang, Chih-Ying, Ma, Yan-Jung, Wei, Kuo-Chen, Yen, Tzu-Chen, Yeh, Chih-Kuang
Format: Artigo
Language:Inglês
Published: Public Library of Science 2014
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4008627/
https://ncbi.nlm.nih.gov/pubmed/24788566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0096327
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