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The Tertiary Origin of the Allosteric Activation of E. coli Glucosamine-6-Phosphate Deaminase Studied by Sol-Gel Nanoencapsulation of Its T Conformer

The role of tertiary conformational changes associated to ligand binding was explored using the allosteric enzyme glucosamine-6-phosphate (GlcN6P) deaminase from Escherichia coli (EcGNPDA) as an experimental model. This is an enzyme of amino sugar catabolism that deaminates GlcN6P, giving fructose 6...

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Bibliografski detalji
Glavni autori: Zonszein, Sergio, Álvarez-Añorve, Laura I., Vázquez-Núñez, Roberto J., Calcagno, Mario L.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2014
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4008608/
https://ncbi.nlm.nih.gov/pubmed/24787711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0096536
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