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In Silico Docking of Forchlorfenuron (FCF) to Septins Suggests that FCF Interferes with GTP Binding

Septins are GTP-binding proteins that form cytoskeleton-like filaments, which are essential for many functions in eukaryotic organisms. Small molecule compounds that disrupt septin filament assembly are valuable tools for dissecting septin functions with high temporal control. To date, forchlorfenur...

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Main Authors: Angelis, Dimitrios, Karasmanis, Eva Pauline, Bai, Xiaobo, Spiliotis, Elias T.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Public Library of Science 2014
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4008567/
https://ncbi.nlm.nih.gov/pubmed/24787956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0096390
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