Continued expression of HPV-16 E7 protein is required for maintenance of the transformed phenotype of cells co-transformed by HPV-16 plus EJ-ras.

The close association between HPV-16 and cervical cancer implies some role for the virus in development of this cancer. Recent studies have shown that the HPV-16 E7 gene encodes the major transforming activity of the virus in baby rat kidney (BRK) cell transformation assays. To investigate the requi...

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Bibliographic Details

Published in:	EMBO J
Main Authors:	Crook, T, Morgenstern, J P, Crawford, L, Banks, L
Format:	Artigo
Language:	Inglês
Published:	Nature Publishing Group 1989
Subjects:	Research Article
Online Access:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC400835/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2542020/ https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1989.tb03405.x
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